There will indeed be anime again this year, and the current plan is to have it back at the Westin as well.
Cosplaying and costumes are a big part of the show, and they're definitely not limited to anime/manga characters. There aren't really any specific rules, beyond the standard safety concerns that all attendees must abide by. Further, crosplaying is certainly allowed as well. No one's going to be double-checking to make sure you are what you're dressed as 
You'll probably want to stop by the anime forum if you have other questions.
Derek Guder - Event Programming Manager
derek@gencon.com | toll-free : 800.529.3976 x111 | direct : 206.957.3811 | cell : 857.389.6675
Have questions about event submission? Gimme a call,
send me an email or stop by the
GM forumI've got a
blog too.